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iPSC Generation

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Resource Type

Normal Organoid

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iPSC Generation

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Others

Artificial Skin

The full name

email@vos.com

Retinal Organoid_main

Normal Organoid

Retinal Organoid

Retinal Organoid_main

Retinal organoids replicate the diverse cell types found in the human retina, allowing for detailed studies of retinal development and function. ▶ Retinal organoids replicate human retina for detailed developmental studies.
They serve as models for studying retinal diseases like retinitis pigmentosa and age-related macular degeneration, aiding in disease understanding and therapeutic development. ▶ Models for retinal diseases aid understanding and therapy development.
Retinal organoids are used to screen potential drugs for retinal disorders, providing a platform to assess drug efficacy and safety in a controlled experimental environment. ▶ Screen drugs for retinal disorders' efficacy and safety accurately.


Organism
Product Type	Organoid
Tissue	iPSC
Disease

Applications

Retinal diseases (such as macular degeneration)

Inflammatory Bowel Disease (IBD) refers to a chronic condition characterized by inflammation within the gastrointestinal tract, causing inflammation of the intestinal walls.

Drug efficacy and toxicity for treatment

Lambda's Intestinal Fibrosis Model addresses these challenges by leveraging high mimetic human intestinal organoids to create a model of inflammatory bowel diseases.

Establishment of retinal organoid differentiation

We successfully developed retinal organoids from human pluripotent stem cells (hPSCs) using advanced differentiation technology.

Analysis of Retinal organoid characteristics and similarity to human anatomy

Retinal organoid structure

The human retina can be broadlydivided into the Neural Retina and Retinal Pigmented Epithelium. We confirmed the expression of specific markers present in each layer of the retina in theretinal organoids. Around 25 days of cultivation, the presence of Retinal Ganglion Cells and Bipolar Cell layers was observed, along with the expression of the specific marker Paired Box Protein-6 (Pax6). Furthermore, by observing changes in cell arrangement within the organoid andexamining the marker for photosensitive cells (Recoverin), we confirmed thesimilarity of the produced retinal organoid to human tissue.

Lambda Biologics

Lambda Biologics

Contact

+49 (0) 152 293 76591

info@lambdabiologics.com

Deutscher Pl. 5c

04103 Leipzig

Germany

@ 2024 . All rights reserved

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Deutscher Pl. 5c

04103 Leipzig

Germany

@ 2024 . All rights reserved

Privacy Policy

Term of Services

Cookie Settings