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GI Tract Disease Model

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Introducing the 3Hs Initiative: Housing, Handling, and Habituation 🏠🐭🧡

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Enhancing Welfare: How to Pick Up a Mouse 🐭✨

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Crafting the Perfect Experiment: Key Elements to Consider 🧪🐭

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Recognizing Pain in Rats: The Rat Grimace Scale 🐭 (The Rat Grimace Scale)

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Understanding Pain through Expressions! 🐰 (The Rabbit Grimace Scale)

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🐭 Observing Facial Expressions to Alleviate Pain! (The Mouse Grimace Scale)

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Arguments Against Animal Research

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When Drugs Pass Animal Tests, But Fail Afterwards

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Understanding Animal Procedures

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How Animal-Free Policies Are Fueling Global Innovation

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Understanding the 3R Principle in Animal Research 🐾

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The Five Myths and Truths About Animal Testing

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Replacing Animal Testing with Stem Cell-Organoids : Advantages and Limitations

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Evolution of Cruelty-Free Testing Methods

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Young Researchers from UK Universities Awarded Lush Prize for Groundbreaking Work in Non-Animal Testing Methods

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Placing Animal Welfare at the Centre of the European Elections

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FDA Modernization Act 2.0 allows for alternatives to animal testing

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🎀Revolutionary Breast Cancer Treatment: New “Breast Cancer-on-Chip” Model for CAR-T Cell Efficacy and Safety Testing

Breakthrough in Nanomaterial Safety Assessment!

The Innovation of Artificial Blood: Bridging the Gap Between “Morbius” and Reality

🖨️Innovative Hybrid 3D Printing Technology for Artificial Organ Production

Revolutionizing Organoid Research with Vascularized Microfluidic Chips

🔬Pioneering the Future of Cancer Research with Advanced Modeling Techniques

Advancements in Brain Research: Unveiling the Blood-Brain Barrier Through Organoid Technology

The Drama’s New Supporting Role, ‘Organoid’

Groundbreaking Research on Human Liver Organoids Offers Hope for Early Detection of Drug-Induced Liver Injury

Vision” Created by Organoids

Revolutionizing Medical Research: The Rise of AI-Enabled Organoids

Designer Immune-cell Therapy Could Shrink Deadly Brain Tumors

Major AlphaFold Upgrade Offers Boost for Drug Discovery

AI Traces Mysterious Metastatic Cancers to Their Source

Antibody Therapy Makes the Immune Systems of Old Mice Young Again

Sebaceous Gland Organoid Engineering

Brain Organoid + Computer = ?

Organoids: Today’s Research Tool, Tomorrow’s Organ Transplant Solution

Newly Developed Organoid Model Can be Used to Study Thymus Function

AI Tool Creates ‘Synthetic’ Images of Cells for Enhanced Microscopy Analysis

Replacing Animal Testing with Stem Cell-Organoids : Advantages and Limitations

Found: The Dial in the Brain that Controls the Immune System

‘ChatGPT for CRISPR’ Creates New Gene-editing Tools

Scientists Made a Six-legged Mouse Embryo — Here’s Why

First Pig Kidney Transplant in a Person: What it Means for the Future

3D-Printed Tumors Replicate Biopsies of Cancer Patients

International Research Team Achieves First-reported, Complete Vascularization of Organoids on Microfluidic Chip

ASU Researcher’s Microscale Tech is Chipping Away at Cancer, Organ Failure and Neurological Disease

Young Researchers from UK Universities Awarded Lush Prize for Groundbreaking Work in Non-Animal Testing Methods

A Human Brain Microphysiological System Derived from Induced Pluripotent Stem Cells to Study Neurological Diseases and Toxicity

A microfluidic platform integrating functional vascularized organoids-on-chip

Prolonged culturing of colonic epithelial organoids derived from healthy individuals and ulcerative colitis patients results in the decrease of LINE-1 methylation level

A suspension technique for efficient large-scale cancer organoid culturing and perturbation screens

Waseda researchers unravel secrets of building better brain organoids with blood vessels

USC Stem Cell scientists develop a game-changing organoid model to study human cerebellar development and disease

Cellular extrusion bioprinting improves kidney organoid reproducibility and conformation

Dynamic matrices with DNA-encoded viscoelasticity for cell and organoid culture

One-step generation of tumor models by base editor multiplexing in adult stem cell-derived organoids

Middle-out methods for spatiotemporal tissue engineering of organoids

Methods for Modeling Development

🛠️Engineered Matrices Reveal Stiffness-Mediated Chemoresistance in Patient-Derived Pancreatic Cancer Organoids

Launch of Clinical Trials in a Dish to Speed Drug Discovery!

Kidney Disease Modeling with Organoids and Organs-on-Chips

🔬Organoid-Based Assessment of Metal-Organic Framework (MOF) Nanomedicines for Ex Vivo Cancer Therapy

GenScript Biotech Corporation Launches FLASH Gene Service: The Fastest and Most Affordable Gene Synthesis Solution on the Market

❤️‍🩹Single-Cell Functional Profiling Using Nanovial Technology Unveils the Therapeutic Potential of Extracellular Vesicles

Tune Therapeutics offers a Genetic Tuning Platform

OrganoIDNet: A Deep Learning Tool for Identification of Therapeutic Effects in PDAC Organoid-PBMC Co-cultures from Time-Resolved Imaging Data

Innovative Gene Therapy Improves Hearing in Two Children

FinalSpark Launches the First Remote Research Platform Using Human Neurons for Biocomputing

First Neuralink Patient Sees Some Implanted Electrodes Lose Connection to Brain

Major AlphaFold Upgrade Offers Boost for Drug Discovery

Generative AI Finds Its Footing in Drug Development

‘ChatGPT for CRISPR’ Creates New Gene-editing Tools

mRNA Drug Offers Hope for Treating a Devastating Childhood Disease

Diabetes Drug Slows Development of Parkinson’s Disease

ASU Researcher’s Microscale Tech is Chipping Away at Cancer, Organ Failure and Neurological Disease

Young Researchers from UK Universities Awarded Lush Prize for Groundbreaking Work in Non-Animal Testing Methods

🫁NF-κB Inhibitor Alpha Controls SARS-CoV-2 Infection in ACE2-Overexpressing Human Airway Organoids

Intestinal Organoids to Model Salmonella Infection and Its Impact on Progenitors!

Utilizing Human Cerebral Organoids to Model Breast Cancer Brain Metastasis in Culture

💧 Lubricant-Coated Organ-on-a-Chip for Enhanced Precision in Preclinical Drug Testing

A Cell Pre-Wrapping Seeding Technique for Hydrogel-Based Tubular Organ-On-A-Chip

💾An Ultrathin Membrane Mediates Tissue-Specific Morphogenesis and Barrier Function in a Human Kidney Chip

Characterization of Patient-Derived Intestinal Organoids for Modelling Fibrosis in Inflammatory Bowel Disease

Azoxymethane-Induced Carcinogenesis-Like Model of Mouse Intestine and Mouse Embryonic Stem Cell-Derived Intestinal Organoids

The First Turtle Organoids

Modeling Blood-Brain Barrier Formation and Cerebral Cavernous Malformations in Human PSC-Derived Organoids

Efficient Hepatocyte Differentiation of Primary Human Hepatocyte-Derived Organoids Using Three Dimensional Nanofibers (HYDROX) and Their Possible Application in Hepatotoxicity Research

Designer Immune-cell Therapy Could Shrink Deadly Brain Tumors

Major AlphaFold Upgrade Offers Boost for Drug Discovery

First Model of the Brain’s Information Highways Developed

AI Traces Mysterious Metastatic Cancers to Their Source

Antibody Therapy Makes the Immune Systems of Old Mice Young Again

Heterozygous RB1 Mutation Enhanced ATP Production in Human iPSC-Derived Retinal Organoids

Synergistic Hyperactivation of Both mTORC1 and mTORC2 Underlies the Neural Abnormalities of PTEN-deficient Human Neurons and Cortical Organoids

Hyaluronan Improves Photoreceptor Differentiation and Maturation in Human Retinal Organoids

High-Fat Diet Enhances Cell Proliferation and Compromises Intestinal Permeability in a Translational Canine Intestinal Organoid Model

Organoids as Advanced Model in Cancer Biology: The Drug Screening and Clinical Applications

Pioneering Technologies Transforming Drug Discovery: From Preclinical Assessments to Clinical Trials

Organoids: Today’s Research Tool, Tomorrow’s Organ Transplant Solution

Newly Developed Organoid Model Can be Used to Study Thymus Function

Scientists Discover New Phage Resistance Mechanism in Phage-bacterial Arms Race

AI Tool Creates ‘Synthetic’ Images of Cells for Enhanced Microscopy Analysis

Liquid Droplets Shape How Cells Respond to Change

Vitamin D Opposes Multilineage Cell Differentiation Induced by Notch Inhibition and BMP4 Pathway Activation in Human Colon Organoids

Endogenous Mutant Huntingtin Alters the Corticogenesis via Lowering Golgi Recruiting ARF1 in Cortical Organoid

Claudin-7 Is Essential for the Maintenance of Colonic Stem Cell Homoeostasis via the Modulation of Wnt/Notch Signaling

FGF7 Enhances the Expression of ACE2 in Human Islet Organoids Aggravating SARS-CoV-2 Infection

Replacing Animal Testing with Stem Cell-Organoids : Advantages and Limitations

Establishment, Characterization, and Biobanking of 36 Pancreatic Cancer Organoids: Prediction of Metastasis in Resectable Pancreatic Cancer

A Pancreatic Cancer Organoid-in-Matrix Platform Shows Distinct Sensitivities to T Cell Killing

Antisense Oligonucleotide Therapeutic Approach for Timothy Syndrome

Spatiotemporally Resolved Colorectal Oncogenesis in Mini-Colons Ex Vivo

A Patient-specific Lung Cancer Assembloid Model with Heterogeneous Tumor Microenvironments

Mini-colon and Brain ‘Organoids’ Shed Light on Cancer and Other Diseases

Found: The Dial in the Brain that Controls the Immune System

UTIs Make Life Miserable — Scientists Are Finding New Ways to Tackle Them

First Fetus-to-fetus Transplant Demonstrated in Rats

Do Cutting-edge CAR-T-cell Therapies Cause Cancer? What the Data Says

‘ChatGPT for CRISPR’ Creates New Gene-editing Tools

Rat Neurons Repair Mouse Brains — And Restore Sense of Smell

How to Supercharge Cancer-fighting Cells: Give Them Stem-cell Skills

mRNA Drug Offers Hope for Treating a Devastating Childhood Disease

Diabetes Drug Slows Development of Parkinson’s Disease

Right- or Left-handed? Protein in Embryo Cells Might Help Decide

Gut Bacteria Break Down Cholesterol — Hinting at Probiotic Treatments

Scientists Made a Six-legged Mouse Embryo — Here’s Why

Memories Are Made By Breaking DNA — And Fixing It

First Pig Kidney Transplant in a Person: What it Means for the Future

Quantifying Y Chromosome Loss in Primary and Metastatic Prostate Cancer by Chromosome Painting

Identification of Genes that Promote PI3K Pathway Activation and Prostate Tumour Formation

In Utero and Postnatal Ivacaftor/Lumacaftor Therapy Rescues Multiorgan Disease in CFTR-F508del Ferrets

SF3B3-regulated mTOR Alternative Splicing Promotes Colorectal Cancer Progression and Metastasis

Modeling Acute Myocardial Infarction and Cardiac Fibrosis Using Human Induced Pluripotent Stem Cell-Derived Multi-Cellular Heart Organoids

‘Mini Liver’ Will Grow in Person’s Own Lymph Node in Bold New Trial

Survival and Functional Integration of Human Embryonic Stem Cell–Derived Retinal Organoids after Shipping and Transplantation into Retinal Degeneration Rats

Blood Vessel Organoids Generated by Base Editing and Harboring Single Nucleotide Variation in Notch3 Effectively Recapitulate CADASIL-Related Pathogenesis

High-Dose Short-Term Osimertinib Treatment Is Effective in Patient-Derived Metastatic Colorectal Cancer Organoids

SARS-CoV-2 Infection Activates Inflammatory Macrophages in Vascular Immune Organoids

3D-Printed Tumors Replicate Biopsies of Cancer Patients

Lifelike Lab-grown Skin Developed from Human Stem Cells

Organoids Research Identifies Factor Involved in Brain Expansion in Humans

International Research Team Achieves First-reported, Complete Vascularization of Organoids on Microfluidic Chip

Establishment of Patient-derived Organoids for Guiding Personalized Therapies in Breast Cancer Patients

Parechovirus Infection in Human Brain Organoids: Host Innate Inflammatory Response and not Neuro-infectivity Correlates to Neurologic Disease

ASU Researcher’s Microscale Tech is Chipping Away at Cancer, Organ Failure and Neurological Disease

Advances and Applications of Cancer Organoids in Drug Screening and Personalized Medicine

cDC2 Plasticity and Acquisition of a DC3-Like Phenotype Mediated by IL-6 and PGE2 in a Patient-Derived Colorectal Cancer Organoids Model

MSCs Alleviate LPS-Induced Acute Lung Injury by Inhibiting the Proinflammatory Function of Macrophages in Mouse Lung Organoid-Macrophage Model

Cholangiocyte Organoids to Study Drug-Induced Injury

Stem Cells Model of Early Human Central Nervous System Created

Bioengineering Toolkits for Potentiating Organoid Therapeutics

Microglial Over-Pruning of Synapses during Development in Autism-Associated SCN2A-Deficient Mice and Human Cerebral Organoids

Efficient Generation of Skin Organoids from Pluripotent Cells via Defined Extracellular Matrix Cues and Morphogen Gradients in a Spindle-Shaped Microfluidic Device

Patient Derived Tumoroids of High Grade Neuroendocrine Neoplasms for More Personalized Therapies

Neuropathogenesis-on-Chips for Neurodegenerative Diseases

Single-Cell Guided Prenatal Derivation of Primary Fetal Epithelial Organoids from Human Amniotic and Tracheal Fluids

Neuromuscular Organoids Model Spinal Neuromuscular Pathologies in C9orf72 Amyotrophic Lateral Sclerosis

Integration of Kupffer Cells into Human iPSC-Derived Liver Organoids for Modeling Liver Dysfunction in Sepsis

Preclinical Efficacy and Safety of Encapsulated Proliferating Human Hepatocyte Organoids in Treating Liver Failure

Deciphering Fibroblast-induced Drug Resistance in Non-small Cell Lung Carcinoma Through Patient-derived Organoids in Agarose Microwells

A Functional Personalised Oncology Approach Against Metastatic Colorectal Cancer in Matched Patient-derived Organoids

In vitro Neurons Learn and Exhibit Sentience when Embodied in a Simulated Game-world

A Human Brain Microphysiological System Derived from Induced Pluripotent Stem Cells to Study Neurological Diseases and Toxicity

Patient-derived Micro-organospheres Enable Clinical Precision Oncology

Blastocyst-like Structures Generated from Human Pluripotent Stem Cells

Evolution of Precision Oncology-guided Treatment Paradigms

Human Salivary Gland Stem Cells Functionally Restore Radiation Damaged Salivary Glands

Organoid-based Regenerative Medicine for Inflammatory Bowel Disease

Establishment and characterization of turtle liver organoids provides a potential model to decode their unique adaptations

Tissue-location-specific transcription programs drive tumor dependencies in colon cancer

A microfluidic platform integrating functional vascularized organoids-on-chip

Generation of complex bone marrow organoids from human induced pluripotent stem cells

Shaping the Neurovascular Unit Exploiting Human Brain Organoids

Organoid Forming Potential as Complementary Parameter for Accurate Evaluation of Breast Cancer Neoadjuvant Therapeutic Efficacy

Effective AAV-Mediated Gene Replacement Therapy in Retinal Organoids Modelling AIPL1-Associated LCA4

Single-cell assessment of primary and stem cell-derived human trophoblast organoids as placenta-modeling platforms

Mitochondrial network physiology disruption during SARS-CoV-2 infection in human lung organoids

Rapid Generation of hPSC-Derived High Endothelial Venule Organoids with In Vivo Ectopic Lymphoid Tissue Capabilities

ER stress and lipid imbalance drive diabetic embryonic cardiomyopathy in an organoid model of human heart development

Integrated characterization of hepatobiliary tumor organoids provides a potential landscape of pharmacogenomic interactions

Mapping the developmental potential of mouse inner ear organoids at single-cell resolution

Analysis of off-tumour toxicities of T-cell-engaging bispecific antibodies via donor-matched intestinal organoids and tumouroids

Urine-derived bladder cancer organoids (urinoids) as a tool for cancer longitudinal response monitoring and therapy adaptation

Prolonged culturing of colonic epithelial organoids derived from healthy individuals and ulcerative colitis patients results in the decrease of LINE-1 methylation level

A suspension technique for efficient large-scale cancer organoid culturing and perturbation screens

Mechanical compartmentalization of the intestinal organoid enables crypt folding and collective cell migration

Waseda researchers unravel secrets of building better brain organoids with blood vessels

USC Stem Cell scientists develop a game-changing organoid model to study human cerebellar development and disease

Brain organoids derived from patients taken to space station

Human Conjunctiva Model Developed For First Time

Novel model of cortical–meningeal organoid co-culture system improves human cortical brain organoid cytoarchitecture

Cellular extrusion bioprinting improves kidney organoid reproducibility and conformation

Network-based machine learning in colorectal and bladder organoid models predicts anti-cancer drug efficacy in patients

Deterministic scRNA-seq captures variation in intestinal crypt and organoid composition

Dynamic matrices with DNA-encoded viscoelasticity for cell and organoid culture

Generation of precision preclinical cancer models using regulated in vivo base editing

One-step generation of tumor models by base editor multiplexing in adult stem cell-derived organoids

Middle-out methods for spatiotemporal tissue engineering of organoids

Methods for Modeling Development

Lambda Biologics

Lambda Biologics

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+49 (0) 152 293 76591

info@lambdabiologics.com

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04103 Leipzig

Germany

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Deutscher Pl. 5c

04103 Leipzig

Germany

@ 2024 . All rights reserved

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Term of Services

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